Complete solution of HPV vaccine ｜ Not about nine-valent HPV vaccine, should we vaccinate bivalent and tetravalent vaccines first？

Cctv news(Reporter Kan Chunyu, Lu Yuanyuan): HPV vaccine has entered the China market for five years, but the public still has many questions about this only vaccine that can prevent cancer. CCTV specially launched a series of programs called "Complete HPV Vaccine" to connect Qiao Youlin, a professor from the School of Medicine and Public Health of Peking Union Medical College and a member of the cancer prevention expert group of WHO Director-General, to dispel the doubts for readers.

1. If the nine-valent HPV vaccine is not available, should the bivalent and tetravalent vaccines be inoculated first?

Qiao Youlin: In fact, a large number of data at home and abroad have proved that the main genotypes causing cervical cancer are 16 and 18, and both bivalent and tetravalent vaccines cover these two genotypes, and tetravalent vaccines also add two low-risk genotypes — — Type 6 and type 11, these two genotypes mainly prevent condyloma acuminatum and other benign diseases.

The preventive effects of these two vaccines on cervical cancer are actually the same. Internationally, everyone’s consensus is that vaccination should be as early as possible, as small as possible and as soon as possible. If there are bivalent seedlings but have to wait for tetravalent seedlings, and there are tetravalent seedlings but have to wait for nine-valent seedlings, there will be eleven-valent seedlings and fourteen-valent seedlings after the nine-valent seedlings. Is it necessary to wait forever?

Nine-valent vaccine has five more genotypes, and its protection coverage can reach more than 90%, but in fact, the risk of cervical cancer in women’s life is not that high, less than 1%. In this case, you can’t wait for a little more protection. In the process of waiting, many women are often infected. In this case, we suggest that you should get whatever vaccine you have.

2. In some areas, girls are vaccinated with HPV free of charge. Why not include adult women?

Qiao Youlin: There are indeed some adult women who are very anxious. They feel that they didn’t get the vaccine before, but now they finally have the vaccine. They should be vaccinated first. In fact, these women should also be vaccinated, especially young women who are sexually active. However, I have to admit that the protective effect of her vaccination is definitely less than 99% and 100%, because she may have been infected before, and the virus may already be in her body. At present, the vaccine has just begun to be popularized and there is still a shortage of supply. I think it is still necessary to vaccinate the most protected girls under the age of 15 with the best immune effect.