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The exterior design of Jetway X95 is fashionable and atmospheric. The front face adopts hexagonal air intake grille, and the interior decoration is chrome-plated horizontal bars, with sharp LED headlights and fog lights, creating a strong sense of movement. The body lines are smooth, the side waistline design is simple and powerful, the rear part is well-defined, and the taillights are designed through, so the overall style is simple without losing the sense of luxury.

Jietu X95 has a body size of 4858*1925*1780mm, a wheelbase of 2850mm, and smooth side lines, showing a stable visual effect. The front and rear wheel tracks are both 1610mm and 1615mm, equipped with 19-inch wheels, and tyre size’s is 235/55 R19, showing a dynamic wheel rim style.

The interior design of Jietu X95 shows the perfect combination of fashion and technology, and the overall style is simple and atmospheric. The steering wheel is made of leather, which feels comfortable, supports manual adjustment up and down and back and forth, and can meet the needs of different drivers. The central control area is equipped with a 12.3-inch large-size touch screen, a rich multimedia system is built in, voice recognition control is supported, and functions such as navigation, telephone, air conditioning and skylight can be easily operated. At the same time, the vehicle also provides two USB interfaces in the front row and the rear row to provide convenient charging requirements for passengers. The seat is made of high-quality imitation leather. The main driver’s seat supports front and rear, backrest and height adjustment, while the co-pilot seat has front and rear and backrest adjustment functions to meet the sitting needs of different passengers. The second row of seats also supports front and rear and backrest adjustment, while the rear seats can also be scaled down to expand the trunk space. In addition, the front row is also equipped with mobile phone wireless charging function, which further enhances convenience.

Jetway X95 is equipped with a 1.6T engine with a maximum power of 145kW (197HP) and a maximum torque of 290Nm. It adopts L4 engine layout and is equipped with a 7-speed wet dual-clutch gearbox.

The price reduction promotion of Jetway X95 provides consumers with a rare opportunity to buy a car. In the current market environment, such preferential activities undoubtedly increase the attractiveness of car purchase. If you are interested in Jetway X95, you may wish to seize this rare opportunity to experience and consult in person in the store, and don’t miss this opportunity to buy a car at a discount.

　　Xinhua News Agency, Nanjing, August 1st Question: Student internship has become a "cash cow" for the school — — Investigation on the chaos of some vocational school students’ internship

　　Xinhua News Agency "Xinhua Viewpoint" reporters Zheng Shengzhu, Feng Songling and Zhao Hongyu

　　Mechanical and electrical engineering students are arranged to sell drinks, and sending a student to an enterprise "internship" can get a thousand yuan "management fee" … … Internship is an important part of the training of skilled personnel in vocational schools. However, the reporter’s investigation found that some vocational schools randomly arrange internship positions unrelated to their majors, and some vocational schools "sell" students to enterprises as cheap labor.

　　The insiders believe that the interest chain behind the internship in vocational schools should be cut off to prevent "school-enterprise cooperation" from becoming "school-enterprise transaction" and let students return to the original intention of teaching.

　　Students complain that the internship position has nothing to do with their major.

　　The "Regulations on the Management of Students’ Internship in Vocational Schools" issued by the Ministry of Education and other five departments clearly requires that internship positions should meet the requirements of professional training objectives and be corresponding to or similar to the majors studied by students.

　　However, recently, many students from Hebei Bohai Polytechnic College told reporters that they were assigned to internship positions unrelated to their majors.

　　A student from the Department of Mechanical and Electrical Engineering of the 2017 class said that on July 17, he was arranged by the school to practice in beijing happy valley. Some of his classmates were cashing in and some were selling drinks, which had nothing to do with their major.

　　On July 16, more than 200 students from the 2017 information engineering department of the school were arranged to do customer service work in an enterprise in Beijing Daxing Yizhuang Economic Development Zone. Because there is no salary and poor accommodation here, some students are unwilling to give up halfway. However, the counselor told them that if the internship is less than 16 weeks, they will be "downgraded" or warned.

　　In response to the mismatch between internship positions and majors, Bohai Polytechnic College responded that students are only experiencing and understanding the positions in the park in Happy Valley. Many students don’t agree with the school’s statement that the practice organized by the school is divorced from the major, which is not helpful to improve the practical ability of the major.

　　It is not uncommon for students from Bohai Polytechnic College to experience internships. The reporter combed and found that many users of Weibo’s remarks for vocational school students have exposed similar internship experiences. Since June this year, People’s Daily Online’s "Local Leaders’ Message Board" has had more than 40 complaints about the mismatch of internship in vocational schools, involving many vocational schools in Shandong, Sichuan, Yunnan and Shaanxi.

　　"One student will give the school 1200 yuan at a time", and the students will become the "cash cow" of the school.

　　In recent years, the Ministry of Education and the education authorities in many places have repeatedly applied for orders, and it is strictly forbidden for schools around the country to transfer benefits between student internships and internship units and labor intermediary agencies, and collect labor fees and agency fees. However, the reporter’s investigation found that some vocational schools still export "student workers" to enterprises or labor agencies, and charge a commission called "management fee".

　　Sharla Cheung (a pseudonym), a 2018 student from School of Information Engineering, Xuchang Vocational and Technical College, Henan Province, introduced that as soon as he finished his studies in June, he and more than 400 students were arranged by the school to work as interns in Wistron Zitong (Kunshan) Co., Ltd., and his job was to attach components, screw, count and package on a mobile phone production line.

　　Many employees of Wistron Zitong (Kunshan) Co., Ltd. revealed that the factory will give some vocational schools a lot of money every year to recruit "student workers". In order to confirm the employee’s statement, the reporter "sought cooperation" from the company in the name of "organizing student internships"; The relevant person in charge of the company’s personnel department said that "students’ majors are not limited" and the company will pay management fees. "There is a large demand for employment in July and August, and a student will give the school 1,200 yuan at a time."

　　Teacher Peng, who is stationed in the college, bluntly said that the current internship position really can’t learn any knowledge and skills professionally, but the state has regulations that vocational colleges must organize students to practice; The school has shortened the internship period from six months to three months, and graduation without internship will be affected.

　　Vocational school students have also become a source of recruitment for some labor intermediary agencies. "It’s not that you give us the agency fee, it’s that we give you the management fee, and every student guarantees the school 800 yuan every month." When the reporter consulted Jiangsu Jiaen Human Resources Service Co., Ltd. as the relevant person in charge of a vocational school in Nanjing, the manager surnamed Sun recommended the internship position of Compal Video (Kunshan) Electronics Co., Ltd. to the reporter. Manager Sun said that the management fee will go with the market, depending on the employment needs of enterprises and the specific composition of students. "The ratio of male to female and the age group are all conditions for us to negotiate with enterprises."

　　Beware of "school-enterprise cooperation" degenerating into "school-enterprise transaction"

　　The insiders believe that some vocational schools send students to some enterprises that have nothing to do with their majors at will, or even make a profit, which deviates from the original intention of vocational education. Departments in charge of education, human resources and social welfare should strengthen the supervision of vocational school practice, cut off the interest chain behind vocational school practice, and prevent "school-enterprise cooperation" from becoming "school-enterprise transaction".

　　Ji Chunlei, vice president of Tongzhou Secondary Vocational School in Jiangsu Province, believes that the school should provide students with sufficient choices, such as organizing job fairs and presentations before internships, so that students, parents and schools can participate together to screen internship positions related to their majors. Schools can’t treat students as cheap labor. For some vocational schools to send students to labor agencies or enterprises for profit, education and other competent departments should find and crack down on them.

　　Xiong Bingqi, vice president of 21st Century Education Research Institute, said that internship training is an important part of vocational education, which requires the school to carefully design, invest corresponding energy and funds, and the competent department should supervise the content and effect of internship in vocational schools. We can explore the establishment of a blacklist system for vocational schools, blacklist vocational schools that violate the rules of internship, and publicize them every year when enrolling students.

　　Wang Hui, a lawyer of Beijing Jingshi Law Firm, believes that the internship organized by vocational schools is an important part of "school-enterprise cooperation", which should not be reduced to "school-enterprise transaction"; In addition to education and other industry authorities should strengthen supervision, labor inspection departments should also strengthen law enforcement to protect the rights and interests of internship students.

　　Chu Zhaohui, a researcher at the Chinese Academy of Educational Sciences, said that the frequent problems of students’ internship mismatch in vocational schools also reflected that some vocational schools failed to adjust their professional settings in time according to the demand of the talent market. It is necessary to deepen the reform of the management system of vocational schools, give vocational schools more autonomy, and improve the matching degree between professional settings and internships and employment positions. (Participating in writing: Ju Hefei)

　　CCTV News:The Central Meteorological Observatory continued to issue a blue warning of severe convective weather at 10: 00 on May 7. It is estimated that there will be 8-10 thunderstorms or hail weather in parts of southeastern Yunnan, southeastern Guangxi, southern Guangdong, northeastern Hainan Island and central and northern Taiwan Province Island from 14: 00 on May 7 to 14: 00 on May 8. There will be short-term heavy rainfall in parts of southeastern Fujian, southeastern Yunnan, southeastern Guangxi, southern Guangdong, most of Hainan Island, and central and western Taiwan Province Island, with an hourly rainfall of 20-40 mm and a local area of more than 60 mm.

　　It is estimated that the main impact period of strong convection is this afternoon.

　　Defense guide:

　　1. The government and relevant departments shall, in accordance with their duties, prepare for short-term rainstorm prevention, lightning protection and gale prevention, and the meteorological department shall prepare for artificial hail suppression;

　　2. Outdoor pedestrians and staff should reduce outdoor activities and pay attention to stay away from structures such as scaffolding billboards;

　　3. Drive poultry and livestock into places with roofs, and close doors and windows to reinforce sheds;

　　4. The water operations in relevant waters and passing ships shall take active measures such as returning to Hong Kong to avoid or detour navigation, pay attention to covering building materials at the construction site, and properly arrange outdoor items susceptible to heavy rain, wind and hail;

　　5. Check the drainage system of cities, farmland and fish ponds, and prepare for drainage and defense against disasters such as mountain torrents, landslides and mudslides.

?　　Foreword　　

In 1993, Belgian scientists discovered a new antibody-nano-antibody (VHHs) in camel serum, which is different from the traditional antibody structure and only consists of heavy chain variable regions. Compared with traditional antibodies, nano-antibodies have the advantages of stable physical and chemical properties, low immunogenicity, strong tissue permeability, and can recognize epitopes that traditional antibodies cannot recognize, which makes them a strong and beneficial supplement to traditional antibodies.

Nano-antibody is only composed of heavy chain variable region, with small molecular weight and simple structure, which enables it to realize stable expression in various expression systems. So far, VHHs has been expressed in many expression systems, from prokaryotic cells, yeast, fungi, insect cells, mammalian cell lines to plants. This paper mainly introduces the expression of nano-antibody in different expression systems, and the present situation and development trend in the field of this system.

Prokaryotic expression system　Prokaryotic expression system is the earliest mature protein expression system studied. Obtaining foreign proteins through prokaryotes can obtain gene expression products in a short time, and the cost required is relatively low. The expression system mainly includes Escherichia coli expression, Bacillus subtilis expression and Streptomyces expression. Among them, Escherichia coli system is the most widely used, and the prokaryotic system generally refers to the expression of Escherichia coli.

Escherichia coli expression system　Escherichia coli expression system is the most important expression platform of recombinant protein in laboratory environment, and the expression is controlled by lactose operon. The host of Escherichia coli system has the advantages of fast growth, simple culture, low price, clear genetic background and high protein expression. However, it can not modify the expression product after translation, and the expression product contains a lot of endotoxin and is easy to form inclusion bodies.

Common host bacteria of Escherichia coli expression system

Periplasmic space, as the only compartment with oxidation environment in Escherichia coli, is the most commonly used expression system of nano-antibodies containing specific disulfide bonds. In addition to aerobic environment, there are many partners and isomerases in the periplasmic space, which can promote the correct formation of disulfide bonds and help protein fold. Nano-antibody protein is first produced in the cytoplasmic space, and then secreted into the periplasmic space through Sec pathway, SPR pathway or Tat pathway. After signal peptide is removed by signal peptidase, the target protein can be obtained [1].

Up to now, many VHHs have been successfully expressed in periplasm, some of which can reach tens of milligrams per liter, but there are still a lot of VHHs with low yield. This is because many fusion proteins can not be effectively secreted in the periplasmic space, and cytoplasmic expression seems to be the only expression mode of such fusion proteins [8].

The cytoplasm is a reduced compartment, so that the proteins expressed through the cytoplasm can not be folded correctly, and most of them are inclusion body proteins. The proteins are protected from the degradation of intracellular enzymes and are easy to be separated in high purity and concentration. However, there are many kinds of proteins in cytoplasm, and it is difficult to purify them. At the same time, nonfunctional inclusion proteins need to be completely denatured and refolded to be recovered from these inclusions, but the recovery of VHHs is usually inefficient [1]. In order to solve the problem of cytoplasmic expression, Xue X and others designed a new dialysis-dilution device in 2016. Using this device, researchers refolded VHHs and achieved a recovery rate of 85%, while the conventional dialysis and dilution methods only reached 13%[9]. Bacterial cytoplasm can be an effective compartment to produce correctly folded nanoparticles when expressed by recombinant vectors with sulfhydryl oxidase and disulfide isomerase activities. Larger volume and wider cytoplasm of chaperone/folding enzyme can achieve high yield of nano-antibody [6]. At the same time, double mutants with defects in thioredoxin and glutathione pathways have been developed. Some of these strains have been sold commercially in recent years, such as Origami (Novagen), Rosetta-gami (Novagen) and SHuffle?T7 (New England Biolabs) [10]. Among them, Shufflet 7 overexpresses a critical periplasmic isomerase DsbC, which can effectively catalyze the isomerization of disulfide bonds. Some studies have found that,The activity of isomerase DsbC can increase the yield of functional recombinant protein in periplasmic research [11].　　

Kavousipour Soudabeh and other modified vectors added four different signal peptide sequences to guide the secretion and expression of nano-antibodies, and found that TrBC signal peptide had the best effect [5]. Jianli Yu et al. used repetitive amino acid sequence motifs (GAGAGS) found in silk fibroin (SFP) as a new fusion tag (SF-tag) to enhance the expression of nanosomes in E.coli.. The transcription level of labeled protein is 2.3-7.0 times that of unlabeled protein, and the yield is increased by 2.5-7.1 times [27]. Xi Xie and others tried to select antifreeze protein AXX, and obtained its reverse transcription protein XXA by synthesizing XXA gene, which was used to develop new soluble fusion tags. It was found that the solubility ratio of fusion protein expressed by XXA fusion tag reached 86%, which was much higher than that of other tags [12].

Other prokaryotic expression systems　Lactic acid bacteria are the most common intestinal probiotics, which are generally considered to be harmless to human body and are very suitable for the production host of therapeutic molecules. However, the existing expression data show that the yield of VHHS produced by lactic acid bacteria is low, about 1-3mg/L, which is much lower than that of Escherichia coli [13,14]. Lactobacillus rhamnosus DSM14870, as a normal flora in human vagina, can express HIV antibody in the form of soluble or cell wall anchor fixation, and is a suitable expression host for HIV antibody [2]. When Bacillus brevis choshinensis was used for 3L fed-batch fermentation, the yield was as high as 3g/L[15]. This system is easy to manipulate genes, has no endotoxin and shows weak protease activity, so it is a very noteworthy system.

Eukaryotic expression system　

Due to the defects of prokaryotic expression system, such as difficult purification of inclusion body protein and incomplete protein modification, people began to use eukaryotic expression system to study genes. At present, eukaryotic expression systems commonly used in genetic engineering research include yeast expression system, insect cell expression system and mammalian cell expression system.

Yeast expression system　Yeast system has clear genetic background, simple operation, easy genetic operation, perfect eukaryotic protein expression control system and advantages of both prokaryotic and eukaryotic expression systems. Yeast eukaryotic protein expression systems include methanol yeast expression system, Saccharomyces cerevisiae expression system, Schizosaccharomyces expression system and Kluyveromyces expression system [17].

Saccharomyces cerevisiae is the first yeast fermented by human beings, which has no specific virus and low cost. At present, it is the largest yeast expression system in shake flask culture, with the output exceeding 100mg/L[16]. Some amino acids in VHHs can participate in the recruitment of molecular chaperones in endoplasmic reticulum, thus narrowing the difference of molecular chaperones between Saccharomyces cerevisiae and mammalian cells, which is beneficial to the folding kinetics of nano-antibodies and improving the yield of nano-antibodies in Saccharomyces cerevisiae [17]. The protein expressed by Saccharomyces cerevisiae is prone to hyperglycosylation, and a large number of endogenous proteins are produced during fermentation, so the secretion efficiency of the target protein is low [1]. Considering the above problems, Saccharomyces cerevisiae is gradually replaced by methanol yeast represented by Pichia pastoris.

Pichia pastoris expression system is an efficient expression system of foreign proteins. This microorganism does not accumulate toxic ethanol, but only secretes a few endogenous proteins, and its glycosylation degree is the same as that of mammalian cells, so its immunogenicity is weak, so it is the most commonly used eukaryotic expression system. Pichia pastoris has a strictly regulated methanol inducible AOX1 promoter, which is suitable for high expression of foreign proteins [1]. But methanol is a highly toxic and dangerous chemical product. The GAP promoter without methanol induction is used instead of AXOI, and the carbon source does not need to be changed during the culture process, so the operation is simpler and the time for foreign proteins to reach the peak level can be shortened. The yield and affinity of nanoparticles produced by this system are similar to those produced by methanol-induced expression. It has been studied that the yield of nano-antibody expressed by this system in shake flask is 51.71mg/L[18] and 16mg/L[19].

Fungal expression system　

Some filamentous fungi, such as Trichoderma and Aspergillus, can secrete a large number of foreign proteins in the culture medium. However, the fungal system not only expresses protein of interest, but also produces many proteases, which affects the yield. Joosten et al. obtained only 1.5 mg/L VHHs in Aspergillus awamori medium. After adding 0.25% BSA, it reached 7 mg/L. It is reported that more than 80% of VHH is degraded or adhered to the cell wall compared with endogenous xylanase secreted efficiently in this system, and researchers believe that the low secretion efficiency of VHHs is the bottleneck of fungal expression [20]. In order to overcome this limitation and protect VHHs from degradation, other researchers fused VHH with the high amylase A signal sequence (sTAA) of Rhizopus oryzae lipase (N28) and the N-terminal 28 amino acid fragment (N28), so that the highest yield of VHHs expressed in Aspergillus oryzae reached 73mg/L, which was 300-800 mg/L lower than that of Escherichia coli [21]. The final yield of GlaB-VHH fusion protein in Aspergillus oryzae can reach 610mg/L, which provides the possibility for high expression of nano-antibody, but its stability needs to be verified [22]. In addition, VHH[23] was expressed by maize head smut in unconventional secretion pathway.

Insect cell expression system　

Insect cells are a widely used eukaryotic expression system, and recombinant baculovirus vectors (such as AcMNPV) can specifically transfect insect cells. Its survival in nature is short, and the strong promoter is inactivated in mammals and cannot infect vertebrates, so the recombinant baculovirus is safe for human beings. Proteins with complex structures under the control of strong promoters may not be able to form correct folding and post-translation modification, which may lead to the aggregation of target proteins and reduce antibody production, so the expression yield of VHHs in this system is much higher than that of other types of antibodies [17].

Gómez-Sebastián and others used the improved baculovirus expression system (IBES? technology) to express VHHs for the first time. The chigger larvae were inoculated with different recombinant baculovirus inoculation methods. The yield of VHH extracted from larvae is 257 mg/L, and the recovery rate after purification is 50%[7]. When expressing anti-endothelial cell selection protein, Drosophila cell SC-2 secreted 12-14mg/L, but the target protein was not detected when expressed in Escherichia coli at the same time, which may be related to the processing and modification ability of insect cells [26].

Mammalian cell expression system　Mammalian cells are the best expression system for therapeutic antibodies, because the produced antibodies have the weakest immunogenicity. At present, the main cell lines include CHO, NS0, Sp2/0, HEK293 and per C6 [17]. Among them, CHO cells grow rapidly and adapt to serum-free suspension culture, which is the most popular host. They can express VHHS up to 100mg/L in shake flask [24]. HEK293 cells are more commonly used in the laboratory because of transient transfection and semi-stable expression, because they require less time and labor. However, monoclonal antibodies approved for the treatment of human diseases are only produced by CHO, NS0 and SP2/0. So far, HEK293 cells have not been used to produce VHHs, and there are few reports about producing antibody fragments by this method [17]. In most literatures, CHO is used to produce antibody fragments. Up to now, 50% of the therapeutic proteins produced in industry are still produced by CHO [1]. The production costs associated with mammalian cell lines are much higher than those associated with any other laboratory research platform.

Common host cells of mammalian expression system

Plant expression system　Compared with other expression systems, plant production platform (stable and transient expression system) is cheap, safe, capable of folding and assembling complex proteins and post-translation modification, easy to expand, and unaffected by human pathogens and diseases. It is an ideal protein expression host and is usually used as an alternative method for mammalian expression systems. In addition, plant expression products can be concentrated in specific organs, such as leaves or seeds, and can be taken orally directly. Tobacco leaves are the most common hosts for expressing VHHs, while the proteins expressed in Arabidopsis and rice seeds have attracted much attention because of their direct oral input of VHHs[1]. The stable transformation methods commonly used in plant system expression have some problems, such as the recombinant gene escaping to nature or the time-consuming transformation. Therefore, some studies have proposed the transient expression system of plant virus expression vector as an alternative method, and the nano-body content with correct conformation reaches 0.45% of the total soluble protein [25].

Present situation and development of nano-antibody expression　

Escherichia coli expression system is the most commonly used expression system of nano-antibody, which has two expression modes: periplasmic expression and cytoplasmic expression, each with its own advantages and disadvantages. Some oxidation engineering strains have been modified, but more experimental support is needed. In addition, various methods of modifying vectors, such as adding labels or signal peptides, have been put forward and have been verified by experiments. Compared with Escherichia coli, Pichia pastoris has excessive glycosylation, which may lead to immunogenicity and ultimately affect its clinical application. The expression systems of fungi, insects, plants and mammals are much more complicated than prokaryotic and eukaryotic expression systems, and are generally not easily adopted after considering the production time, cost and laboratory conditions.

Escherichia coli system is fast, convenient and cheap, and it is the first choice for VHH expression under most laboratory conditions. When some types of VHHs can’t be successfully produced in E.coli, other systems will be used instead.

List of nano-antibody expression

　　Future Network, Beijing, February 7 (Reporter Zhou Xin) At 23: 51 pm on February 6, Xiao ‘an, a girl from Guangzhou who was traveling in Taipei, received an emergency alarm from the earthquake. Ten seconds later, her hotel began to shake, and she and her friends immediately opened the door and rushed downstairs. After gathering with other tenants downstairs for more than half an hour, they chose to go back to their residence because the temperature was too low. Ann and her friends decided to sleep in shifts. However, one night, the earthquake continued, and Xiao An dared not sleep.

　　Xiao ‘an is 22 years old, a senior student and a painter. In early February, during the winter vacation, she started a 9-day and 8-night trip to Taiwan Province with her friends. "Because there were many exhibitions in Taiwan Province before the Chinese New Year, I made an appointment with my friends to come and watch comic-con exhibitions and the like, which just happened to meet Taiwan Province, a classmate I met before."

　　Xiao An and his friends live in a hotel on Xining South Road, Wanhua District, Taipei. Before the earthquake, they had just returned to their residence from the night market in Ximending and were reading a book. She was a little confused when she saw that the mobile phone received the earthquake warning information, but then it shook off guard, which made her and her friends subconsciously run away. "At that time, there was an alarm on the mobile phone about 10 seconds in advance, and we were all confused. Suddenly the building shook and it shook for a long time." Xiao An lives on the sixth floor. When she went downstairs, she noticed that all the tenants were running out at the same time. And the streets are full of people who ran out.

　　In the third minute after the earthquake, Xiao An sent her mother a WeChat, telling her that she had encountered an earthquake. My mother was very worried. She kept asking her what to do, whether she had food or not, and told her to bring water. When my friend’s parents learned the news of the earthquake, they wanted them to change their plane tickets to go home. Xiao An and his friends originally scheduled to go home on the 11th, but before leaving, they thought they could play for one more day, so they changed their air tickets to the 12th. There was an earthquake this time, and Xiao An thought it was impossible to change the visa. "It is estimated that it is unlikely. Now many people want to change their visas."

　　After gathering downstairs for half an hour, the crowd gradually dispersed because of the cold weather. "I can hear dogs barking nearby, and most shops in the street are closing. I went to a convenience store with my friends. Many people were waiting in line to buy food, and everyone was bowing their heads and returning their mobile phone messages. " Xiao An told reporters.

　　Since returning to his residence, Xiao An has been watching the earthquake report on TV. "In fact, there was an earthquake the day before yesterday. At that time, the subway and the train stopped, but there was no feeling in Taipei. We thought it was a small earthquake, and Taiwan Province’s friends also said not to worry. " She told Future.com that she didn’t expect the earthquake to be so serious. "I dare not turn off the TV. I still feel very serious. Several buildings in Hualien are tilted. Although the landlord said that there is no need to be afraid of frequent earthquakes, because the hotel is old and has a wooden structure, it is still very worried. " Ann and her friends decided to sleep in shifts and go down as soon as something happened.

　　At 2 o’clock in the morning on the 7 th, Xiao An told reporters that he felt another obvious aftershock. She began to worry about her trip for the next few days. "I originally planned to go to Jiufen Mountain on the 8 th, and the homestays have been booked. Now I am hesitant and feel unsafe. It may be safer to stay in Taipei."

　　At 3: 16 in the morning, Xiao An told reporters, "It was shocked again, and the shaking was obvious. I am afraid, but I am so sleepy. " Xiao An said that although everyone went back to the room, it was obvious that everyone in the surrounding room was talking and didn’t sleep.

　　According to the China Seismological Network, a 6.5-magnitude earthquake occurred at 23: 50 on February 6 in the waters near Hualien County, Taiwan (24.13 degrees north latitude and 121.71 degrees east longitude) with a focal depth of 11 kilometers. Since then, several earthquakes have occurred at 2: 00, 3: 00 and 4: 00 on the 7 th.

　　According to Xinhua News Agency, as of 5: 00 on the 7th, the Hualien 6.5 earthquake in Taiwan has killed two people and injured 202 others. According to the news of the Taiwan Fire Department at 5 am on the 7th, 149 people have been rescued, and 2 shelters have been opened to accommodate 354 people.

　　In addition to Xiao ‘an and other tourists, many Taiwan Province netizens also told the reporter of Future.com that the earthquake in Taipei, which is more than 100 kilometers away from Hualien, was obvious and swayed from side to side.

　　"I hope that the trip will come back safely now." Xiao An said.

On December 16th, Lectra Auto officially announced that its 08 EM-P car will soon push the Lynk Flyme Auto version 1.7.0 update. This update contains a number of new features and optimizations to enhance the user experience.

The updated contents include: supporting DC charging above -30℃ to enhance the charging ability in low temperature environment; App remote vehicle control function, which is convenient for users to operate vehicles remotely; The heating opening rate of the steering wheel is improved to improve the driving comfort in winter; The map accurately shows the countdown to the next traffic light, which can provide accurate information even in the road without green waves; HUD displays steering tips to enhance driving safety; STR ultra-electric quick start function improves the convenience of vehicle starting; The seat adjustment interface is optimized, from side view to top view, which is more intuitive and easy to understand; Harman Kardon virtual venue returns, and the panoramic sound of WANOS is preserved to enhance the sound experience; Add a cloud listening App to enrich the car entertainment content.

This update is expected to bring a smarter and more convenient driving experience to the owners of Lectra 08 EM-P.

Hualong News (Qi Che) Recently, Kia of yueda announced the launch of EV5 limited-time welfare package. From now until April 30th, consumers can enjoy three years’ financial benefits with 0 down payment and 0 interest when purchasing Kia EV5. In addition, you can also enjoy multiple benefits such as warranty, interconnection, maintenance and replacement of the three power plants and the whole vehicle, with a comprehensive benefit of up to 40,000 yuan.

Specifically, when consumers buy EV5, they can enjoy the financial rights of 0 down payment and 0 interest for 3 years, and the financial discount is as high as 23,000 yuan, which greatly reduces the threshold for consumers to buy a car, which can be described as full of sincerity. In addition, users who purchase EV5 can also enjoy the 8-year or 150,000-kilometer warranty of Sanpower, 5-year or 100,000-kilometer warranty of the whole vehicle, 7,000 yuan replacement subsidy, 5-year free unlimited full data traffic, 5-year free basic maintenance materials, and the opportunity to get a limited number of car purchase rights such as rear cabin air cushions. Not only that, Kia’s old car owners can also get a 2-year compulsory insurance or a 2-year charging card (2,600 yuan /2 years); Consumers can enjoy an additional 5,000 yuan cash subsidy or 5,000 yuan "Happy Purchase" small program coupons donated by yueda Group when buying a car, and the maximum discount can reach 40,000 yuan.

EV5 is a model specially launched by Kia for its 80th anniversary, and it is also the core model of Kia’s electrification transformation. Based on KIA’s world-leading E-GMP platform for electric vehicles, EV5 has a pure and tough appearance design, an efficient three-electric system, a long cruising range of 720km, a flexible and practical ever-changing space, a healthy and environmentally-friendly intelligent cabin, a high-level intelligent driving system and luxurious and comfortable and convenient configuration, bringing users a pure electric travel experience that exceeds expectations.

In terms of the most important three-electric system of pure electric products, EV5 has also shown proud advantages, especially the long-life version of EV5, which has a long pure electric cruising range of 720km, and the charging time from 30% to 80% is only 27 minutes, which can meet the needs of multi-scenarios such as urban commuting or long-distance travel. EV5 also comes standard with a heat pump air conditioning system, a battery temperature control management system, and the only five-level adjustable intelligent kinetic energy recovery system at the same level, which effectively improves power consumption.

In terms of intelligent technology configuration, the EV5 720 is equipped with a 27-inch integrated triple screen, and the long-life version also provides an 11.3-inch head-up display to create an immersive driving experience of "four-screen linkage", and has also cooperated with Baidu and Tencent to develop more than 30 practical apps. In terms of intelligent driving, EV5 has reached L2+ level, and has 18 highly intelligent driving assistance configurations, such as front collision prevention assistance II with active braking and active avoidance, highway driving assistance with automatic lane change by shifting lever, intelligent parking assistance with barrier-free parking in all scenes, collision prevention assistance in blind areas, collision prevention assistance in rear crossing, and safety exit assistance, etc., which can be said to protect safe travel to the extreme.

As a heavy strategic vehicle launched in China and facing the world, Kia EV5 not only carries out R&D and design according to the needs of consumers in China, but also exports to the world with high-quality product value. On April 1st, EV5 export models also began to be mass-produced in Yancheng 4.0 Intelligent Manufacturing Factory and sold to developed markets around the world such as Australia.

　　For users who often travel with the whole family, they will definitely give priority to seven-seat or large six-seat models, but they often find that the third row of many cars is either too small and impractical, or too expensive. Then, you might as well consider it. It will tell you with facts what is really big six-seat and what is comfortable and equal rights.

　　Yipai eπ 008 is the second model launched after the eπ 007 (sedan). It is positioned as a home intelligent large SUV and has two power forms: pure electric and range extension. The body length is more than 5 meters, the wheelbase is more than 3 meters, and it is a really large six-seat, and the internal space is quite generous. Dongfeng Yipai eπ 008 is expected to sell for between 20-250,000 yuan, and has a quite high quality and price ratio among the same-class models. It is expected to be officially delivered in June.

　　Let’s talk about the size of Dongfeng Yipai e π 008. The length, width and height of the body are: 5002 * 1972 * 1732mm, and the wheelbase is 3025mm. You can buy a large SUV of this size at a price 200,000, which is enough to be exciting. The appearance design of Dongfeng Yipai e π 008 is very atmospheric, and the length of 5 meters is quite impressive from the visual experience.

　　In terms of details, the intelligent starlight grille that supports a variety of welcome rhythm display effects, coupled with the through-through headlights composed of 536 LEDs that echo back and forth, is also full of fashion and technology.

　　From the side, the Yi Pai e π 008 adopts a flat roof design, and the area of the C-pillar small window is also quite large, which brings a longer visual length and also gives more vision to the third row, which does not make people feel depressed. The design of the lower waist line adds a little sense of agility to the side of the body, and at the same time, the chrome decorative strips running through the front and rear enhance more luxury. The Yi Pai e π 008 also uses hidden door handles, which makes the body feel stronger and reduces some wind resistance. The wind resistance coefficient of the whole vehicle is 0.268Cd.

　　The EPI 008 uses 21-inch low-drag wheels, which are matched with Continental low-roll-resistance silent tires, with a tire size of 265/45 R21. These four tires alone are worth a lot of money, and it does not cost money. It does greatly improve the comfort and silence of the whole vehicle.

　　The D-pillar side window is equipped with an LED indicator light to display the battery level when charging.

　　The tail design of the Yi Pai e π 008 is relatively full, and the decorative lines picked on both sides of the bumper add some sports elements. The through tail lights and the characteristic lines of the license plate area create a more three-dimensional sense of hierarchy.

　　The interior of the Yipai eπ 008 is a more composed style and is more durable. With a 15.6-inch central LCD screen and an 8.8-inch LCD instrument panel, the car is equipped with an 8155 chip, and the content displayed on the car interface can be seen.

　　The cockpit leather is made of 100% environmentally friendly water-based surface treatment, and the center console is made of Benecke suede PVC material, which feels excellent. The suede material absorbs strong light, and the shadow of the interior does not reflect on the front windshield. This is indeed better than what some luxury brands do.

　　The car-machine interface is not only visible, but also has gesture control functions. In addition, the automatic speech recognition ability of Yipai eπ 008 is very accurate, and it can also determine whether the voice is sent from the front or the back, so as to accurately identify the front and rear functions that need to be controlled.

　　The 9.2-inch streaming rearview mirror shows clearly, and the reflection is very weak. When the rear roof entertainment screen is turned on, the ordinary optical rearview mirror will be blocked by the screen. At this time, the streaming rearview mirror is very necessary, and it can be regarded as a safety configuration.

　　The front 50W mobile phone wireless fast charging, with ventilation function, Honor mobile phone can reach the level of extremely fast charging, basically charging for 1 minute, and the mobile phone power increases by 1%.

　　In addition to buying a large SUV, 200,000 people can also buy a refrigerator, color TV, and a large sofa. The Yipai eπ 008 is equipped with a 15.6-inch rear entertainment screen, which can be opened through the rear touchscreen or voice. For children, the rear entertainment screen can make them quiet faster, and for adults, long-distance travel will not be particularly boring.

　　The upper and lower dual touch screens in the rear row can adjust the heating and ventilation of the seats and the nap mode in the rear row; the touch screens below adjust the cooling and warmth of the refrigerator and move back and forth.

　　Yipai eπ 008 uses a semiconductor refrigeration refrigerator with a minimum temperature of 5 ° C and a maximum temperature of 50 ° C. It has an electric front and rear movement function and can be stopped on the slide at any time, making it convenient for passengers in the second and third rows to pick up drinks and items.　　

　　Of course, Yi Pai e π 008 also has a big sofa – a zero-gravity seat, in addition to supporting ventilation and heating, it also has a massage function, making long-distance travel more comfortable.

　　Yipai eπ 008 benefits from the 3025mm wheelbase, which makes the interior of the vehicle have a large "housing rate" of 67.4%. The direct benefit is that it has 6 large sofa seats, and everyone’s comfort is a mobile home.

　　In terms of details, Yi Pai e π 008’s control is also very good. There are 28 + 2 storage spaces in the whole car, and each row of passengers has its own exclusive cup holder. The trunk space can be flexibly arranged through baffle, which is really attentive.

　　The test drive this time is the Yipai eπ 008 pure electric version, which uses a 200kW rear single motor. From the actual driving experience, it is very easy to drive such a large SUV. The power reserve is good, even if the speed reaches 120km/h, the power can still be stepped on. The steering wheel is pointed more accurately, and the whole car is very flexible and does not feel bulky.

　　The most commendable thing is that the quietness of the whole vehicle is excellent, and it also meets the demands of family car users. With the blessing of Continental silent tires, double front windshield, double front and rear window glass, and the excellent NVH design and materials of the vehicle itself, it is almost impossible to hear obvious fetal noise and wind noise when driving at high speed.

　　Another commendable feature was the suspension tuning. Yi Pai E Pi 008 actually used the coil spring + shock absorber to adjust the feeling of the air spring. The fine road vibration was filtered very thoroughly, and the sharp bounce could be resolved in time.

　　Yipai eπ 008 is based on Dongfeng quantum architecture and is equipped with Dongfeng Mach E electric drive system. The maximum efficiency of the electric drive assembly is 94.5%. The comprehensive energy consumption of the pure electric model is as low as 14.7kwh/100km, and the CLTC battery life reaches 636km. In addition, the extended range model is equipped with the industry’s first extended range dedicated engine with a thermal efficiency of 45.18%. The CLTC pure electric battery life is 210km, the feed fuel consumption is as low as 5.55L/100km, and the CLTC comprehensive battery life is 1300km.

　　Yipai eπ 008 is equipped with 32 high-precision sensing hardware, including a black sesame A1000 chip, which supports high-speed NOA pilot auxiliary driving and has functions such as automatic up and down ramp and automatic lane change, which belongs to the level of L2 + intelligent driving.

　　With the launch of the eπ 007 medium and large sedan and the eπ 008, which will be officially launched in June, Dongfeng Yipai will continue to make efforts in the two power tracks of pure electricity and range extension, and compete head-on with mainstream new energy brands in the 15-250,000 level market. Looking forward to the future Dongfeng Yipai will bring more dazzling products and bring more new energy vehicle choices to consumers.

[Autohome Jinzhong Promotion Channel] Good news! In the Jinzhong area, Toyota is running a high-profile promotion. This high-profile SUV model is now attracting consumers with up to 45,000 discounts, and the minimum selling price has been adjusted to 124,800. This is a rare car purchase opportunity. If you want to know more about specific models and lock in your favorite price, don’t miss it. Click the "Check the car price" button in the quotation form to hurry up and act!

The RAV4 Rongfang is striking with its unique front face design, and the iconic air intake grille adopts the fusion of modernity and power, showing the essence of the Toyota brand. The overall style is stylish and atmospheric, with smooth lines, giving a steady and dynamic visual impact. Whether it is a city shuttle or an outdoor adventure, it can attract everyone’s attention.

The Toyota RAV4 is modern with its sleek body design and streamlined side lines. The body size is 4600mm*1855mm*1680mm and the wheelbase is up to 2690mm, providing a spacious foundation for the interior space. The layout of the front wheelbase of 1605mm and the rear wheelbase of 1620mm guarantees good driving stability. The tire size is 225/65 R17, and it is paired with a stylish wheel design, which is not only practical, but also adds to the sporty atmosphere of the vehicle. Overall, the side design of the RAV4 Rongfang is both beautiful and practical.

The interior design of the RAV4 Rongfang focuses on the coexistence of practicality and comfort, creating a spacious and refined sense of space. The delicate plastic steering wheel feels lightweight and supports manual up, down, and front and rear adjustments, which is convenient for the driver to control accurately. The 10.25-inch central control screen is clear and easy to operate, with integrated multimedia functions. USB and Type-C interfaces are distributed in the front row, which is convenient for passengers to connect to electronic devices. The seats are made of fabric, and the main and auxiliary seats are equipped with multi-directional adjustment functions, including front and rear, backrest and height adjustments, to meet the individual needs of passengers. The second row of seats also supports backrest adjustment, while the rear seats support proportional reclining, providing flexibility for cargo. The overall interior layout is both practical and detail-oriented, providing a pleasant in-car experience for drivers and passengers.

The RAV4 is equipped with a 2.0L displacement four-cylinder engine with a maximum power of 126 kW and a peak torque of 206 Nm. With 171 horsepower output, this engine is coupled with a CVT continuously variable transmission (analog 10th gear), providing the driver with a smooth and efficient power experience.

Summarizing the evaluation of Autohome owners, RAV4 Rongfang left a deep impression with its solid body structure and unique design style. He emphasized the vehicle’s frame skeleton and waist design, as well as the domineering front face, which undoubtedly enhance the driver’s confidence and driving stability. For consumers who pursue individuality and practicality, RAV4 Rongfang is undoubtedly a choice worth considering.

[Autohome Changzhou Promotion Channel] brings you the latest car purchase benefits! In the bustling city of Changzhou, the Mercedes-Benz brand is conducting a powerful promotion. At present, the maximum discount has reached an amazing 111,000 yuan, which brings the starting price of this high-performance luxury SUV down to an attractive 1.0598 million yuan. If you are interested in this passionate and luxurious Mercedes-Benz AMG SUV, don’t miss this once-in-a-lifetime opportunity. Click "Chatti Car Price" in the quotation form to act now and put your dream car within reach at a lower price. Take advantage of this great opportunity to reduce the price and experience the ultimate driving experience brought by AMG!

The Mercedes-Benz GLE coupe AMG presents an unparalleled sporty aesthetic with its unique design language. On the front face, the iconic AMG air intake grille is as sharp as the tusks of a beast, and with the carefully carved front bumper, it gives the vehicle a strong sense of power. The body lines are smooth and powerful, and the back-running design not only enhances the visual impact, but also shows the perfect combination of elegance and dynamics. The overall style is very sporty, and every detail shows the AMG brand’s persistent pursuit of performance and aesthetics.

The AMG Mercedes-Benz GLE coupe is uniquely dynamic and powerful with its streamlined side design. The body length is 4944mm, the width is 2018mm, the height is 1716mm, and the wheelbase is 2935mm, creating a solid body ratio. The smooth and sculptural lines on the side show the AMG brand’s deep understanding of sports aesthetics. The front wheels are equipped with 275/45 R21 tires, and the rear wheels are equipped with wider 315/40 R21 tires, which not only enhances the driving stability, but also adds to the visual impact of the vehicle. The overall design not only focuses on performance, but also pays more attention to the refinement and luxury of details.

The interior design of the Mercedes-Benz GLE Coupe AMG reflects the perfect fusion of luxury and performance. The refined leather material and the steering wheel are wrapped in leather and inlaid with carbon fiber elements, which not only feels delicate to the touch, but also brings a strong sense of movement. The 12.3-inch central control screen stands in front of the driver, clearly displaying multimedia information, navigation and vehicle data, and supports automatic speech recognition for easy operation. The seats, whether in the driver’s or passenger’s seat, are equipped with electric adjustment functions, including front and rear, backrest, high and low and waist support, to ensure ultimate comfort. The front seats also have additional heating and ventilation functions, as well as electric memory functions, which highlight the details of luxury. At the same time, the rear seats support proportional reclining, providing flexible space utilization for passengers and luggage. The overall interior design is both practical and sporty, showcasing the unique interior charm of Mercedes-AMG models.

The Mercedes-Benz GLE Coupe AMG is equipped with a powerful 3.0T turbocharged engine that can output up to 435 horsepower and peak torque of 560 Nm. This power unit is paired with a 9-speed automatic transmission, ensuring excellent performance and driving pleasure.

After summarizing the full text about the excellent performance, unique design and excellent driving experience of the Mercedes-Benz GLE Coupe AMG, we are pleased to learn that in order to give back the support and love of the majority of fans, Mercedes-Benz is now launching a limited-time promotion. In this preferential policy, Mercedes-Benz GLE Coupe AMG is fortunate to enjoy a large market discount, making the dream of owning this high-performance SUV even more within reach. Don’t miss the opportunity, time will never come again. Now is the perfect time for you to experience the ultimate charm of Mercedes-Benz AMG. Seize this opportunity and make Mercedes-Benz GLE Coupe AMG the king’s choice on your road. For more details, please pay attention to Mercedes-Benz official channels or dealers, and ride with speed and passion to ride the future together.